Projects

Research projects from Oulu, Copenhagen and Aarhus.

ADHD x obesity shared genetics

Active

2024-09 - present

Investigating shared genetic architecture and biological mechanisms between ADHD and obesity using polygenic scoring, Mendelian randomisation, PheWAS, and integrative genomics across biobank-scale cohorts.

Role: Lead analyst (postdoc)

SBayesRC polygenic risk scoringBidirectional Mendelian randomisationPheWAS across 1,434 ICD-10 phecodesMiXeR, LAVA, LDSC genetic correlationASSET and METASOFT cross-trait meta-analysisFUMA, MAGMA, FINEMAP, PoPS, FLAMES gene prioritisation+2

Manuscript in preparation (first author)
Oral presentation, ESHG Annual Meeting 2025
Upcoming presentation, World Congress of Psychiatric Genetics, Glasgow, September 2026

2025-06 · ESHG 2025 oral presentation2026-09 · WCPG Glasgow presentation

Genetics of insulin sensitivity and T2D

Completed

2021-06 - 2024-11

PhD research establishing the genetic architecture of insulin sensitivity and its links to type 2 diabetes, obesity, and cardiovascular disease, using GWAS of 21 indices in Danish cohorts.

Role: PhD researcher

GWAS of 21 insulin sensitivity indicesGenetic risk score developmentCross-cohort validation (adult to paediatric)

Three first-author publications
PhD thesis submitted and defended

Genetic Underpinnings of Fasting and Oral Glucose-stimulated Based Insulin Sensitivity Indices Adult-based Genetic Risk Scores for Insulin Resistance Associate With Cardiometabolic Traits in Children and Adolescents Exploring the genetic intersection between obesity-associated genetic variants and insulin sensitivity indices

Cancer functional genomics, Oulu

Completed

2017-01 - 2019-08

Functional genomics of prostate and breast cancer susceptibility loci in the Gong-Hong Wei lab, combining wet-lab experiments with statistical and computational GWAS follow-up analysis.

Role: Research assistant / MSc researcher

ChIP-seq, RNA-seq, CRISPR-Cas9SNPs-seqeQTL and pathway enrichment analysis

Published in Cell, Nature Communications, and Cancer Research

Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer

Trisk 95 skin glucose biomarker

Completed

2018-06 - 2019-08

Identified a skin-based protein biomarker (Trisk 95/Triadin) mirroring systemic blood glucose in a type 1 diabetic mouse model, in the Vainio Laboratory of Developmental Biology, Oulu.

Role: Researcher; performed the promoter luciferase reporter study

Molecular cloning and luciferase reporter assayPrimary keratinocyte cultureIn vivo STZ-induced diabetic mouse model

Published in Scientific Reports, 2020

Trisk 95 as a novel skin mirror for normal and diabetic systemic glucose level

Interested in any of these projects? Email me