Oxidative stress markers

Computes GSH_GSSG_Ratio = reduced glutathione (GSH) / oxidized glutathione (GSSG).

Usage

oxidative_markers(
  data,
  col_map = list(GSH = "GSH", GSSG = "GSSG"),
  na_action = c("keep", "omit", "error"),
  verbose = FALSE
)

Arguments

data

Data frame with columns for GSH and GSSG (per col_map).

col_map

Named list with required keys GSH and GSSG. Defaults assume same names.

na_action

One of c("keep","omit","error").

verbose

Logical; if TRUE, emits progress via hm_inform().

Value

A tibble with column GSH_GSSG_Ratio.

References

Forman HJ, Zhang H, Rinna A (2009). “Glutathione: Overview of its protective roles, measurement, and biosynthesis.” Molecular Aspects of Medicine, 30(1–2), 1–12. doi:10.1016/j.mam.2008.08.006 .

Examples

df <- data.frame(GSH = c(5, 3), GSSG = c(1, 0.5))
oxidative_markers(df, col_map = list(GSH="GSH", GSSG="GSSG"))
#> # A tibble: 2 × 1
#>   GSH_GSSG_Ratio
#>            <dbl>
#> 1              5
#> 2              6