Calculates the ratio of appendicular lean mass (ALM) to body mass index (BMI), and flags low muscle mass based on FNIH Sarcopenia Project cut-points.
Arguments
- data
A data.frame or tibble with ALM, BMI, and sex columns.
- col_map
Named list with:
alm: appendicular lean mass column name (kg)
bmi: body mass index column name (kg/m^2)
sex: sex column name ("Male"/"Female" or m/f; case-insensitive)
- verbose
Logical; if TRUE, emits progress messages.
- na_action
One of c("keep","omit","error","ignore","warn").
- check_extreme
Logical; if TRUE, scan inputs for plausible ranges.
- extreme_action
One of c("warn","cap","error","ignore","NA").
- extreme_rules
Optional list with bounds for
almandbmi(defaults: alm = c(5, 40), bmi = c(10, 60)).
Value
A tibble with:
alm_bmi_ratio (numeric)
low_muscle_mass (logical; TRUE if below sex-specific cut-point; NA if sex unknown or ratio NA)
Details
ALM/BMI reflects muscle mass relative to body size. FNIH cut-points:
Men: ALM/BMI < 0.789
Women: ALM/BMI < 0.512
ALM should be in kilograms and BMI in kg/m^2.
References
McLean RR, Shardell MD, Alley DE, et al. (2014). “Criteria for clinically relevant weakness and low lean mass: FNIH Sarcopenia Project.” Journal of Gerontology A: Biological Sciences and Medical Sciences, 69(5), 576–583. doi:10.1093/gerona/glu012 . ; Studenski SA, Peters KW, Alley DE, et al. (2014). “The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates.” Journal of Gerontology A: Biological Sciences and Medical Sciences, 69(5), 564–570. doi:10.1093/gerona/glu010 .
Examples
df <- data.frame(ALM_kg = c(7.2, 5.8, 6.5), BMI = c(24, 28, 22),
Sex = c("male", "female", "male"))
alm_bmi_index(df)
#> # A tibble: 3 × 2
#> alm_bmi_ratio low_muscle_mass
#> <dbl> <lgl>
#> 1 0.3 TRUE
#> 2 0.207 TRUE
#> 3 0.295 TRUE